Decoding the brain’s functional alphabet-Jin Hyung Lee, PhD-02/10/2015 - 6:00pm

Event Information
Event Topic: 
Decoding the brain’s functional alphabet
Event Date: 
02/10/2015 - 6:00pm
Event Location: 
Wilson Sonsini Goodrich & Rosati, 650 Page Mill Road, Palo Alto CA
Speaker Information
Event Speaker: 
Jin Hyung Lee, PhD
Event Speaker Title: 
Assistant Professor of Neurology, of Neurosurgery and of Bioengineering and, by Courtesy, of Electrical Engineering
Event Speaker Company: 
Stanford University
Event Speaker Bio: 

The Lee Lab uses interdisciplinary approaches from biology and engineering to analyze, debug, and manipulate systems-level brain circuits. We seek to understand the connectivity and function of these large-scale networks in order to drive the development of new therapies for neurological diseases. This research finds its basic building blocks in areas ranging from medical imaging and signal processing to genetics and molecular biology.

Dr. Lee is a recipient of the 2010 NIH/NIBIB R00 Award, the 2010 NIH Director's New Innovator Award, the 2010 Okawa Foundation Research Grant Award, the 2011 NSF CAREER Award, the 2012 Alfred P. Sloan Foundation Research Fellowship Award, and the 2013 Alzheimer's Association New Investigator Award.

Event Details
$6 - Students/In-transition - Members only
$11 - Early-bird Registration - Members only
$20 - Late Registration and Non-Members
$25 - Walk-ins
Event Details: 

Understanding the functional communication across brain has been a long sought-after goal of neuroscientists. However, due to the widespread and highly interconnected nature of brain circuits, the dynamic relationship between neuronal network elements remains elusive. With recent development of optogenetic functional magnetic resonance imaging (ofMRI), it is now possible to observe whole-brain level network activity that results from modulating with millisecond-timescale resolution the activity of genetically, spatially, and topologically defined cell populations. ofMRI uniquely enables mapping global patterns of brain activity that result from the selective and precise control of neuronal populations. Advances in the molecular toolbox of optogenetics, as well as improvements in imaging technology, will bring ofMRI closer to its full potential. In particular, the integration of ultra-fast data acquisition, high SNR, and combinatorial optogenetics will enable powerful systems that can modulate and visualize brain activity in real-time. ofMRI is anticipated to play an important role in the dissection and control of network-level brain circuit function and dysfunction. In this talk, the ofMRI technology will be introduced with advanced approaches to bring it to its full potential, ending with examples of dissecting neurological disease circuits utilizing ofMRI.